Cynomolgus Integrin alpha 11 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free | IT1-C53W3-1mg

Cynomolgus Integrin alpha 11 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free | IT1-C53W3-1mg| Gentaur Distribution US, UK & Europe

Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.

Source: Cynomolgus ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-C53W3) is expressed from CHO cells. It contains AA Phe 23 - Pro 1131 & Gln 21 – Asp 728 (Accession # A0A2K5U8X4-1 & XP_005564990.1).

Format: Powder.

Tag: C-10×His | Native.

Expression System: CHO.

Expression Region: Phe 23 - Pro 1131 & Gln 21 – Asp 728.

Conjugate: Unconjugated.

Molecular Weight: 131.4 kDa & 83.6 kDa.

Characteristics: Cynomolgus ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 131.4 kDa & 83.6 kDa. The protein migrates as 105-115 kDa and >170 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT