Cynomolgus IL-12 R beta 1 Protein, Fc Tag | ILB-C5253-1mg

Cynomolgus IL-12 R beta 1 Protein, Fc Tag | ILB-C5253-1mg| Gentaur Distribution US, UK & Europe

The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Source: Cynomolgus IL-12 R beta 1 Protein, Fc Tag (ILB-C5253) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Asp 545 (Accession # G7PWY9-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Cys 24 - Asp 545.

Conjugate: Unconjugated.

Molecular Weight: 83.9 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.9 kDa. The protein migrates as 110-120 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT