Description
Cynomolgus Cadherin-17 / CDH17 Protein, His Tag | CA7-C52H4-100ug| Gentaur Distribution US, UK & Europe
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Source: Cynomolgus Cadherin-17, His Tag (CA7-C52H4) is expressed from human 293 cells (HEK293). It contains AA Lys 30 - Thr 792 (Accession # A0A2K5X8I8-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Lys 30 - Thr 792.
Conjugate: Unconjugated.
Molecular Weight: 86.6 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 86.6 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 85%.
Buffer: 20 mM Tris, 150 mM NaCl, 0.5 M Arginine, pH8.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
