Cynomolgus ASGR1 Protein, His Tag | AS1-C5243-100ug

Cynomolgus ASGR1 Protein, His Tag | AS1-C5243-100ug| Gentaur Distribution US, UK & Europe

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

Source: Cynomolgus ASGR1 Protein, His Tag (AS1-C5243) is expressed from human 293 cells (HEK293). It contains AA Ser 61 - Leu 291 (Accession # XP_005582755.1).

Format: Powder.

Tag: N-10×His.

Expression System: HEK293.

Expression Region: Ser 61 - Leu 291.

Conjugate: Unconjugated.

Molecular Weight: 28.3 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 37-42 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4, 0.2M Arginine.

Storage Conditions: -20℃.

Shipping Conditions: RT