Description
CRE/CREB Reporter (Luc) - Jurkat Cell Line (cAMP/PKA Signaling Pathway) | 79636 | Gentaur US, UK & Europe Disrtribition
Category: Cell Line/Reporter Cell Line & Cell-Based Assays
Application: Monitor cAMP/PKA signaling pathway activity and screen for activators or inhibitors of cAMP/PKA signaling pathway.
Background: N/A
Description: The CRE/CREB Reporter (Luc) - Jurkat Cell Line contains a firefly luciferase gene under the control of multimerized cAMP response element (CRE) stably integrated into Jurkat cells. Elevation of the intracellular cAMP level activates cAMP response element binding protein (CREB) to bind CRE and induces the expression of luciferase. This cell line is validated for response to stimulation by Forskolin.
Product Type: Cell line
Shippement Condition: -80°C