CEACAM6 CHO Cell Line | 78550

CEACAM6 CHO Cell Line | 78550 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: • Screen antibodies for immunotherapy research • Characterize CEACAM6 antibodies and ligands • Study the biological function of CEACAM6

Background: CEA cell adhesion molecule 6 (CEACAM6, also known as CD66c) is a glycosyl phosphatidyl inositol (GPI)-anchored cell surface glycoprotein that serves as a cell adhesion protein. CEACAM6 is considered a clinical biomarker and candidate therapeutic target in melanoma, lung, colorectal, and pancreatic cancers. It may play a role in tumor progression through regulation of cell migration, invasion, and anoikis, promoting metastasis. It is also known to affect the sensitivity of tumor cells to adenovirus infection, and it serves as a receptor for E. coli adhesion to the surface of intestinal cells in patients with Crohn's disease.

Description: Recombinant CEACAM6 CHO K1 cell line stably expressing the full-length human CEACAM6 receptor (accession number: NM_002483). Surface expression of hCEACAM6 was confirmed by flow cytometry. Each stable clonal cell line was selected for high level of hCEACAM6 expression compared to its parental CHO K1 cells.

Product Type: Cell Line

Shippement Condition: -80°C