CEA Antibody / Carcinoembryonic Antigen | V2087SAF-100UG

CEA Antibody / Carcinoembryonic Antigen | V2087SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: COL-1

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This CEA antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The COL-1 antibody recognizes proteins of 80-200kDa, identified as different members of the Carcinoembryonic Antigen family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This antibody does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. CEA antibody is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are positive) from pleural mesotheliomas (rarely or weakly positive). CEA antibody positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Immunogen: Human colon carcinoma extract was used as the immunogen for this CEA antibody.

Storage: Store the CEA antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).