CD73, Avi-His-Tag (Mouse) | 72523

CD73, Avi-His-Tag (Mouse) | 72523 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Protein

Application: Useful for studying enzyme kinetics, substrate specificity, and screening inhibitors.

Background: CD73, or cluster of differentiation 73, is an enzyme which hydrolyzes AMP to adenosine. Increased concentrations of adenosine in the microenvironment has an immunosuppressive effect and promotes tumor cell growth.

Description: Mouse CD73, also known as 5'-nucleotidase and Ecto-5'-nucleotidase, GenBank Accession No. NM_011851, a.a. 29-549 with C-terminal Avi-His-tag, expressed in a HEK293 cell expression system. MW = 61 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Product Type: Protein

Shippement Condition: -80°C