CD4 Antibody | V8352-100UG

CD4 Antibody | V8352-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: GK1.5

Host Animal: Rat

Clonality: Monoclonal (rat origin)

Species Reactivity: Mouse

Application: ELISA, Neutralization, FACS, IF

Buffer: N/A

Limitation: This CD4 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

Immunogen: Mouse CTL clone V4 was used as the immunogen for the CD4 antibody.

Storage: Store the CD4 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).