CD31 Antibody / PECAM-1 | V8257SAF-100UG

CD31 Antibody / PECAM-1 | V8257SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: PECAM1/3527

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, IHC-P, WB

Buffer: N/A

Limitation: This CD31 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Immunogen: A recombinant human partial protein (amino acids 625-738) was used as the immunogen for the CD31 antibody.

Storage: Store the CD31 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).