Cathepsin E Antibody / CTSE | F54422-0.08ML

Cathepsin E Antibody / CTSE | F54422-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, FACS, IHC-P

Buffer: N/A

Limitation: This CTSE antibody is available for research use only.

Purity: Antigen affinity purified

Description: CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.

Immunogen: A portion of amino acids 157-187 from the human protein was used as the immunogen for the CTSE antibody.

Storage: Aliquot the CTSE antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.