Description
Cathepsin E Antibody / CTSE | F54422-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, FACS, IHC-P
Buffer: N/A
Limitation: This CTSE antibody is available for research use only.
Purity: Antigen affinity purified
Description: CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
Immunogen: A portion of amino acids 157-187 from the human protein was used as the immunogen for the CTSE antibody.
Storage: Aliquot the CTSE antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
