Canine TROP-2 / TACSTD2 Protein, His Tag | TR2-C52H4-100ug

Canine TROP-2 / TACSTD2 Protein, His Tag | TR2-C52H4-100ug| Gentaur Distribution US, UK & Europe

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

Source: Canine TROP-2, His Tag (TR2-C52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 39 - Thr 281 (Accession # XP_852842.5).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gln 39 - Thr 281.

Conjugate: Unconjugated.

Molecular Weight: 29.4 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.4 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT