c-Kit Antibody / CD117 | V2649SAF-100UG

c-Kit Antibody / CD117 | V2649SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: KIT/983

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This c-Kit antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This mAb recognizes a protein of 145kDa, identified as CD117/p145kit/c-Kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117/c-Kit has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117/c-Kit is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.

Immunogen: A recombinant human fragment around amino acids 100-300 was used as the immunogen for the c-Kit antibody.

Storage: Store the c-Kit antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).