Biotinylated Mouse CD200 / OX-2 Protein, Fc, Avitag™ (MALS verified) | OX2-M82F3-200ug

Biotinylated Mouse CD200 / OX-2 Protein, Fc, Avitag™ (MALS verified) | OX2-M82F3-200ug| Gentaur Distribution US, UK & Europe

CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

Source: Biotinylated Mouse CD200, Fc, Avitag (OX2-M82F3) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gly 232 (Accession # O54901-1).

Format: Powder.

Tag: C-Fc & C-Avi.

Expression System: HEK293.

Expression Region: Gln 31 - Gly 232.

Conjugate: Biotin-labeled.

Molecular Weight: 50.5 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 50.5 kDa. The protein migrates as 66-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT