Biotinylated MERS Spike Trimer Protein, His, Avitag™ (MALS verified) | SPN-M82E3-200ug

Biotinylated MERS Spike Trimer Protein, His, Avitag™ (MALS verified) | SPN-M82E3-200ug| Gentaur Distribution US, UK & Europe

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: Biotinylated MERS Spike Trimer Protein, His, Avitag (SPN-M82E3) is expressed from human 293 cells (HEK293). It contains AA Tyr 18 - Trp 1295 (Accession # K9N5Q8-1 (R748A, R751A, V1060P, L1061P, K1284Q) ).

Format: Powder.

Tag: C-10×His & C-Avi.

Expression System: HEK293.

Expression Region: Tyr 18 - Trp 1295.

Conjugate: Biotin-labeled.

Molecular Weight: 147.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 147.6 kDa. The protein migrates as 180-210 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS.

Storage Conditions: -20℃.

Shipping Conditions: RT