BCL2 Monoclonal Antibody | E-AB-22004

BCL2 Monoclonal Antibody | E-AB-22004 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Mouse

Isotype: IgG

Application: WB, IHC-p

Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction

Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Protein A purification

Dilution: WB 1:1000-2000, IHC 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 26 kDa

Observed Molecular Weight: 26 kDa

Clonality: Monoclonal