Description
BAX Polyclonal Antibody | E-AB-40495 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC-P
Research Area: Cancer, Cell Biology, Metabolism
Background: BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction . BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria . The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis .
Lead Time: 7~10 days
Concentration: 0.566mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of Human Apoptosis regulator BAX
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification: Antigen Affinity Purification
Dilution: WB 1:1000-1:3000, IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 21 kDa
Observed Molecular Weight: 21 kDa
Clonality: Polyclonal
