Basic Cytokeratin Antibody (HMW / Type II) | V2329-100UG

Basic Cytokeratin Antibody (HMW / Type II) | V2329-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: AE3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, FACS, IHC-P, IF

Buffer: N/A

Limitation: This Basic Cytokeratin antibody AE3 is available for research use only. The formulation is not suitable for therapeutic or diagnostic testing.

Purity: Protein G purified

Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Many studies have shown the usefulness of keratin markers in cancer research and tumor diagnosis. The basic family clone AE3 is commonly used in combination with clone AE1 as a pan cytokeratin antibody acidic + basic cocktail (Cat No V2330).

Immunogen: Solubilized cytokeratin extract from human stratum corneum was used as the immunogen.

Storage: Store the Basic Cytokeratin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).