B7-H6 Antibody / NCR3LG1 | V8734-100UG

B7-H6 Antibody / NCR3LG1 | V8734-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: B7H6/4821

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This B7-H6 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.

Immunogen: A portion of amino acids 38-169 from the human protein was used as the immunogen for the B7-H6 antibody.

Storage: Store the B7-H6 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).