APEX1 Polyclonal Antibody | E-AB-10130

APEX1 Polyclonal Antibody | E-AB-10130 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, ELISA

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling

Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Lead Time: 7~10 days

Concentration: 0.1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human APEX1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 36 kDa

Observed Molecular Weight: N/A

Clonality: Polyclonal