Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) | S1N-M130-1mg

Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) | S1N-M130-1mg| Gentaur Distribution US, UK & Europe

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Source: AntiN/ASARSN/ACoVN/A2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (S1NN/AM130) is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified recombinant SARSN/ACoVN/A2 Spike S1 Protein. This antibody can broadly recognize all Variants of Concerns (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2) and Omicron (B.1.1.529) .

Molecule: Spike RBD.

Species: Mouse.

Tag: Human IgG1 | Human Kappa.

Conjugate: Unconjugated.

Purity: 95%.

Charactirization: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT