Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (Trehalose free) | NUN-S47-1.5mg

Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (Trehalose free) | NUN-S47-1.5mg| Gentaur Distribution US, UK & Europe

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68) . The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

Source: AntiN/ASARSN/ACoVN/A2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (NUNN/AS47) was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified recombinant SARSN/ACoVN/A2 Nucleocapsid protein. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. ELISA test validated that this antibody can bind multiple N protein variants (Cat. No. NUNN/AC52H8, NUNN/AC52Hc, NUNN/AC52Hd, NUNN/AC52Hm, NUNN/AC52H6, NUNN/AC52H3, NUNN/AC52H9, NUNN/AC52H4) with similar affinity as compared to the wild type N protein (Cat. No. NUNN/AC5227) .

Molecule: Nucleocapsid protein.

Species: Mouse.

Tag: Mouse IgG1 | Mouse Kappa.

Conjugate: Unconjugated.

Purity: 95%.

Charactirization: PBS, pH7.4.

Storage Conditions: 2-8℃.

Shipping Conditions: Blue ice