Anti-PD-1 (S228P) Antibody | 71326

Anti-PD-1 (S228P) Antibody | 71326 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Antibody

Application: Useful for inhibition of PD-1:PD-L1 and PD-1:PD-L2 interactions

Background: This antibody binds and blocks the activation of the PD-1 receptor. The antibody is humanized, containing a human IgG4 Fc region with an engineered hinge region mutation (S228P) designed to prevent the exchange of IgG4 molecules. This antibody is equivalent to Nivolumab, which has been approved by the FDA for the treatment of melanoma and metastatic squamous non-small cell lung cancer.

Description: Humanized recombinant anti-PD-1 (IgG4) antibody with S228P mutation, expressed in HEK293 cells. This antibody has not been tested with other species.

Product Type: Antibody

Shippement Condition: -80°C