AMPK Antibody (PRKAA1) | F50188-0.08ML

AMPK Antibody (PRKAA1) | F50188-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This AMPK antibody is available for research use only.

Purity: Purified

Description: AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. It appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. AMPK alpha 1, a member of the Ser/Thr protein kinase family, is a catalytic subunit of AMPK.

Immunogen: A portion of amino acids 479-510 from the human protein was used as the immunogen for this AMPK antibody.

Storage: Aliquot the AMPK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.