AF647 Anti-Human CD20 Antibody | DL22248F-4

AF647 Anti-Human CD20 Antibody | DL22248F-4 | Gentaur US, UK & Europe Disrtribition

Synonyms: Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1

Reactivity: Human

Host: Mouse

Application: FCM

Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn) . It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Concentration: N/A

Conjugation: AF647

Buffer: PBS with 0.05% Proclin300, 1% BSA

Isotype: Mouse IgG2b, κ

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.