AF/LE Purified Anti-Human CD11a Antibody | DL22231F-1

AF/LE Purified Anti-Human CD11a Antibody | DL22231F-1 | Gentaur US, UK & Europe Disrtribition

Synonyms: Integrin alpha-L,LFA-1A,CD11A,ITGAL

Reactivity: Human

Host: Mouse

Application: FA,FCM

Background: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Concentration: 0.5 mg/mL

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: Mouse IgG1, κ

Storage: Store at 2~8°C. Do not freeze.