Actin Antibody (pan muscle) | V3100IHC-7ML

Actin Antibody (pan muscle) | V3100IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: MSA/953

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Rat

Application: IHC-P

Buffer: N/A

Limitation: This pan Muscle Actin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes actin of skeletal, cardiac, and smooth muscle cells. It is not reactive with other mesenchymal cells except for myoepithelium. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-muscle specific actin recognizes alpha and gamma isotypes of all muscle groups. Non-muscle cells such as vascular endothelial cells and connective tissues are non-reactive. Also, neoplastic cells of non-muscle-derived tissue such as carcinomas, melanomas, and lymphomas are negative. It stains tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).

Immunogen: An amino acid sequence common among human skeletal, cardiac and smooth muscle actins was used as the immunogen for the pan Muscle Actin antibody.

Storage: Store the pan Muscle Actin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).