ABI2 Antibody | R31179

ABI2 Antibody | R31179 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: N/A

Limitation: This ABI2 antibody is available for research use only.

Purity: Antigen affinity

Description: ABL Interactor 2 is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein; a central serine-rich region; three PEST sequences, which are implicated in susceptibility to protein degradation; several proline-rich stretches; and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.

Immunogen: An amino acid sequence from the N-terminus of human ABL Interactor 2 (RFKVSTQNMKMGGLPR) was used as the immunogen for this ABI2 antibody (100% homologous in human, mouse and rat).

Storage: After reconstitution, the ABI2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.