Description
AAV-DJ Luciferase-mCherry | 78469 | Gentaur US, UK & Europe Disrtribition
Category: Viral Tools/AAV
Application: • Use as a positive control for transduction • Optimize transduction assays and track protein expression over time
Background: N/A
Description: Adeno-Associated Virus-DJ (AAV-DJ) is a synthetic serotype made from eight different wild-type AAV serotypes (AAV2, 4, 5, 8, 9, avian, bovine, and goat AAV) using DNA shuffling. These modifications give the AAV-DJ serotype improved transduction efficiency in vitro and in vivo compared to wild-type serotypes. Consequently, AAV-DJ can infect a broad range of cell types. These AAV particles constitutively express the firefly (Photinus pyralis) luciferase and mCherry genes connected via a T2A linker, under the control of a CMV promoter. The T2A self-cleaving peptide (derived from Thosea asigna virus 2A) leads to the efficient cleavage of the transcript, and expression of luciferase and mCherry as two separate proteins.
Product Type: AAV virus
Shippement Condition: -80°C
