AANAT Antibody | F51822-0.08ML

AANAT Antibody | F51822-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This AANAT antibody is available for research use only.

Purity: Antigen affinity

Description: Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

Immunogen: A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.

Storage: Aliquot the AANAT antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.