Description
AANAT Antibody | F51822-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, ELISA
Buffer: N/A
Limitation: This AANAT antibody is available for research use only.
Purity: Antigen affinity
Description: Serotonin N-acetyltransferase/AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
Immunogen: A portion of amino acids 27-54 from the human protein was used as the immunogen for this AANAT antibody.
Storage: Aliquot the AANAT antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
