14-3-3 sigma Antibody / SFN | V3999-100UG

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SKU:
800-V3999-100UG
Size:
100 ug
€984.00
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Description

14-3-3 sigma Antibody / SFN | V3999-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: CPTC-SFN-2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, IHC-P

Buffer: N/A

Limitation: This 14-3-3 Sigma antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: SFN (Stratifin), also called 14-3-3 Sigma, is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.

Immunogen: Full length recombinant human protein was used as the immunogen for the 14-3-3 Sigma antibody.

Storage: Store the 14-3-3 Sigma antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

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