Description
14-3-3 sigma Antibody / SFN | V3999-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Format: Purified
Clone: CPTC-SFN-2
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This 14-3-3 Sigma antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: SFN (Stratifin), also called 14-3-3 Sigma, is a p53-induced tumor suppressor gene which is activated in response to DNA damage, causing cell cycle arrest at G2 phase by blocking cdc2-cyclin B1 complex from entering the nucleus. It is inactivated in breast, lung, prostate, liver and gastric cancer. It is associated with poor prognosis when its down-regulation is observed in epithelial ovarian cancer. SFN expression could contribute to cancer cell proliferation and the development and/or progression of human gastrointestinal cancer.
Immunogen: Full length recombinant human protein was used as the immunogen for the 14-3-3 Sigma antibody.
Storage: Store the 14-3-3 Sigma antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
