Description
ZIC2 Polyclonal Antibody | E-AB-53238 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Application: IHC, ELISA
Research Area: Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Background: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Lead Time: 7~10 days
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human ZIC2
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: IHC 1:50-1:200, ELISA 1:2000-1:5000
Conjugation: Unconjugated
Calculated Molecular Weight: N/A
Observed Molecular Weight: N/A
Clonality: Polyclonal