Description
ZIC2 Antibody | RQ6448 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IF, FACS, Direct ELISA
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This ZIC2 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Zinc finger protein ZIC2 is a protein that in humans is encoded by the ZIC2 gene. This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Immunogen: Recombinant human protein (amino acids A31-Y214) was used as the immunogen for the ZIC2 antibody.
Storage: After reconstitution, the ZIC2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
