ZHX3 Antibody | V8872-20UG

ZHX3 Antibody | V8872-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: PCRP-ZHX3-1D11

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA, IP, WB, FACS

Buffer: N/A

Limitation: This ZHX3 antibody is available for research use only.

Purity: Protein A/G affinity

Description: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Immunogen: Recombinant full-length human ZHX3 protein was used as the immunogen for the ZHX3 antibody.

Storage: Aliquot the ZHX3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.