Description
ZEB2 Antibody (SIP1) | R31649 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This ZEB2 antibody is available for research use only.
Purity: Antigen affinity
Description: Zinc finger E-box-binding homeobox 2, also known as SIP1 or Zinc finger homeobox 1B (ZFHX1B), is a protein that in humans is encoded by the ZEB2 gene. The gene is a member of the ZEB1/Drosophila Zfh1 family of two-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activatedSMADs, the transducers ofTGF-betasignaling, and interacts with the nucleosome remodeling and histone deacetylation (NURD) complex. By radiation hybrid analysis, this gene is mapped to 2q22. It has been found that synthesis of ZEB2 was upregulated followingSNAI1expression in human cell lines, and the expression of SNAI1 in epithelial cells can trigger an epithelial-mesenchyme transition.
Immunogen: Human partial recombinant protein (AA 1-200) was used as the immunogen for this ZEB2 antibody.
Storage: After reconstitution, the ZEB2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
