Description
XRN1 Antibody | F53814-0.05ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 1647CT536.85.48
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: WB
Buffer: N/A
Limitation: This XRN1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: 5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Immunogen: A human recombinant protein corresponding to amino acids 1455-1706 was used as the immunogen for the XRN1 antibody.
Storage: Aliquot the XRN1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
