XRN1 Antibody | F53814-0.05ML

XRN1 Antibody | F53814-0.05ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1647CT536.85.48

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This XRN1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: 5'-3' Exoribonuclease 1 is a major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Immunogen: A human recombinant protein corresponding to amino acids 1455-1706 was used as the immunogen for the XRN1 antibody.

Storage: Aliquot the XRN1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.