XRCC4 Antibody | F46899-0.08ML

XRCC4 Antibody | F46899-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This XRCC4 antibody is available for research use only.

Purity: Antigen affinity

Description: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq].

Immunogen: A portion of amino acids 205-234 from the human protein was used as the immunogen for this XRCC4 antibody.

Storage: Aliquot the XRCC4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.