Description
XRCC1 Antibody | F49231-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, FACS, IF, ELISA
Buffer: N/A
Limitation: This XRCC1 antibody is available for research use only.
Purity: Antigen affinity
Description: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Immunogen: A portion of amino acids 407-435 from the human protein was used as the immunogen for this XRCC1 antibody.
Storage: Aliquot the XRCC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.