WT1 Antibody / Wilms Tumor 1 | V8926-20UG

WT1 Antibody / Wilms Tumor 1 | V8926-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: WT1/3477R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 1-2ug/ml

Application Note: Optimal dilution of the recombinant Wilms Tumor 1 antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: The WT1 gene located at chromosome 11p13 codes for a transcription factor, a DNA-binding nucleoprotein, that plays a role primarily in the development of genitourinary organs. There are at least eight isoforms ranging between 52 and 62kDa produced by a combination of alternative splicing and RNA editing. WT1 is synthesized and reside in the cytoplasm in an inactive form. When activated through phosphorylation it is translocated to the nucleus.

Immunogen: A portion of amino acids 1-100 was used as the immunogen for the recombinant Wilms Tumor 1 antibody.

Storage: Aliquot the recombinant Wilms Tumor 1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Nucleus and cytoplasm