Description
WT1 Antibody / Wilms Tumor 1 | V8926-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: WT1/3477R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the recombinant Wilms Tumor 1 antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: The WT1 gene located at chromosome 11p13 codes for a transcription factor, a DNA-binding nucleoprotein, that plays a role primarily in the development of genitourinary organs. There are at least eight isoforms ranging between 52 and 62kDa produced by a combination of alternative splicing and RNA editing. WT1 is synthesized and reside in the cytoplasm in an inactive form. When activated through phosphorylation it is translocated to the nucleus.
Immunogen: A portion of amino acids 1-100 was used as the immunogen for the recombinant Wilms Tumor 1 antibody.
Storage: Aliquot the recombinant Wilms Tumor 1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Nucleus and cytoplasm
