Description
Wnt-C59 | 27780-3 | Gentaur US, UK & Europe Disrtribition
Category: Inhibitors / Activators/Other
Application: N/A
Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase), thereby blocking Wnt protein secretion and activity, similar to Wnt inhibitors IWP-2, IWP-3 and IWP-4. But Wnt-C59 is more potent and selective, and has better chemical/physical properties, and is more suitable for in vitro/in vivo studies.
Description: Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.
Product Type: Inhibitor
Shippement Condition: Room temp. (continental US) or gel packs
