Description
WNK3, GST-Tag | 100973 | Gentaur US, UK & Europe Disrtribition
Category: Kinase-Serine/Threonine/Protein
Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Background: WNK3 is a member of serine-threonine protein kinases, which was named the with-no-lysine family. WNK3 is expressed in several tissues including kidney and brain. WNK3 can regulate the activity of the electroneutral cation-coupled chloride cotransporters by activating NKCC1/2 and NCC and inhibiting KCCs. WNK3 kinase function is required for normal blood pressure homeostasis and the control of neuronal excitability. Also, overexpression of WNK3 increases the survival of Hela cells through caspase-3 pathway.
Description: N/A
Product Type: Protein
Shippement Condition: -80°C
