Description
WISP1 Antibody | R31201 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-P, IHC-F, ICC
Buffer: N/A
Limitation: This WISP1 antibody is available for research use only.
Purity: Antigen affinity
Description: WNT1-Inducible Signaling Pathway Protein 1, also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene. It is induced by WNT1 and belongs to the CCN family, which includes connective tissue growth factor, cysteine-rich-61, and nephroblastoma overexpressed(Tanaka et al., 2001). By use of radiation hybrid mapping panels, Pennica et al.(1998) mapped the gene to chromosome 8q24.1-q24.3, roughly 4 Mb distal to MYC. Pennica et al.(1998) found that two distinct systems demonstrated that WISP1 induction was associated with expression of WNT1. WISP1 genomic DNA was amplified in colon cancer cell lines and in human colon tumors, and its RNA was overexpressed in 84% of tumors examined compared with patient-matched normal mucosa.
Immunogen: An amino acid sequence from the C-terminus of human WNT1-Inducible Signaling Pathway Protein 1 (ADLESYPDFSEIAN) was used as the immunogen for this WISP1 antibody.
Storage: After reconstitution, the WISP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
