WFDC1 Antibody | F54651-0.08ML

WFDC1 Antibody | F54651-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC-P, WB, FACS

Buffer: N/A

Limitation: This WFDC1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Immunogen: A portion of amino acids 148-177 from the human protein was used as the immunogen for the WFDC1 antibody.

Storage: Aliquot the WFDC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.