von Willebrand Factor Antibody / vWF | V2298SAF-100UG

von Willebrand Factor Antibody / vWF | V2298SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: 3E2D10

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB, IP, IHC-P

Buffer: N/A

Limitation: This vWF antibody is available for research use only.

Purity: Protein G purified vWF antibody

Description: von Willebrand Factor is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This vWF antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi�s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Immunogen: Amino acids 845-949 were used as the immunogen for this vWF antibody.

Storage: Store the vWF antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).