von Willebrand Factor Antibody | R31686

von Willebrand Factor Antibody | R31686 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse, Rat

Application: WB, IHC-P

Buffer: N/A

Limitation: This von Willebrand Factor antibody is available for research use only.

Purity: Antigen affinity

Description: Von Willebrand Factor is a blood glycoprotein involved in hemostasis. The VWF gene encodes a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. vWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. Deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.

Immunogen: Mouse partial recombinant protein (AA 1304-1452) was used as the immunogen for this von Willebrand Factor antibody.

Storage: The von Willebrand Factor antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaws.