VLDLR Antibody / VLDL Receptor | V8163SAF-100UG

VLDLR Antibody / VLDL Receptor | V8163SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: VLDLR/2896R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG, kappa

Species Reactivity: Human

Application: ELISA

Application Details: ELISA (order BSA-free format for coating)

Application Note: Optimal dilution of the antibody should be determined by the researcher.

Purity: Protein A affinity chromatography

Description: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Immunogen: A recombinant protein fragment from the C-terminal region of VLDLR was used as the immunogen for this recombinant VLDL Receptor antibody.

Storage: Store the recombinant VLDL Receptor antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).

Localization: N/A